KEGG   Schizosaccharomyces pombe (fission yeast): SPCC162.09c
Entry
SPCC162.09c       CDS       T00076                                 
Symbol
hmg1
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-CoA reductase Hmg1
  KO
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Organism
spo  Schizosaccharomyces pombe (fission yeast)
Pathway
spo00900  Terpenoid backbone biosynthesis
spo01100  Metabolic pathways
spo01110  Biosynthesis of secondary metabolites
Module
spo_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:spo00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    SPCC162.09c (hmg1)
Enzymes [BR:spo01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)
     SPCC162.09c (hmg1)
SSDB
Motif
Pfam: HMG-CoA_red Sterol-sensing HPIH Orthoreo_P10
Other DBs
NCBI-GeneID: 2538999
NCBI-ProteinID: NP_588235
PomBase: SPCC162.09c
Ensembl: SPCC162.09c
UniProt: Q10283
Position
III:1561184..1565491
AA seq 1053 aa
MIYKLAARYPIQVIAIVGILVSMAYFSFLEALTQEDFPVLIRALKRFGILDGFPNTRLPN
EMILKLSSVQGEDASVWEQIPAAELGGEGFVDFDITQWYYPANAKVDVAQLVEPYRNDCI
FHDASGACHFFFKEVGNWTVSSIALPSNLANPPIDYFLDSSSTVIQRILPAIREHGISWS
WLLQLIARTWMNTLKIASQASKTELLIVGTAYACMLISIVSLYLKMRRLGSKFWLFFSVL
LSTLFSVQFAMTLVRASGVRISLVSLIESLPFLINVVALDKAAELTRQVITRCSVSDSHS
PMHEDIAKACRNAAPPILRHFSFGIVVLAIFSYCNFGIKQFFLFAAVMIYDLLLLFSFFV
AILTLKLEMRRYNAKDDVRKVLIEEGLSESTARHVADGNDSSATTSAGSRYFKVRYGTKI
ILFIFIAFNLFELCSIPFKHYAATSAAAARLIPLVRSQYPDFKSQRLLDDGVFDDVLSAI
SSMSNIESPSVRLLPAVFYGAELSSTSFLSTIHSFINNWSHYISASFLSKWIVCALSLSI
AVNVFLLNAARLNSIKEEPEKKVVEKVVEVVKYIPSSNSSSIDDIQKDEIAQESVVRSLE
ECITLYNNGQISTLNDEEVVQLTLAKKIPLYALERVLKDVTRAVVIRRTVVSRSSRTKTL
ESSNCPVYHYDYSRVLNACCENVIGYMPLPLGVAGPLIIDGKPFYIPMATTEGALVASTM
RGCKAINAGGGAVTVLTRDQMSRGPCVAFPNLTRAGRAKIWLDSPEGQEVMKKAFNSTSR
FARLQHIKTALAGTRLFIRFCTSTGDAMGMNMISKGVEHALVVMSNDAGFDDMQVISVSG
NYCTDKKPAAINWIDGRGKSVIAEAIIPGDAVKSVLKTTVEDLVKLNVDKNLIGSAMAGS
VGGFNAHAANIVTAVYLATGQDPAQNVESSNCITLMDNVDGNLQLSVSMPSIEVGTIGGG
TVLEPQGAMLDLLGVRGAHMTSPGDNSRQLARVVAAAVMAGELSLCSALASGHLVKSHIG
LNRSALNTPAMDSSAKKPATDALKSVNSRVPGR
NT seq 3162 nt   +upstreamnt  +downstreamnt
atgatttataaacttgctgctcggtatccaattcaagtgattgccattgtgggcatcctt
gtctctatggcatatttttccttcttggaagccttaactcaagaagatttcccagtatta
attcgtgctttaaaacgatttggtattttggatggatttccgaacactcgtctacctaac
gagatgattttaaagctaagtagtgtccaaggtgaggatgcctcggtttgggaacaaatt
cctgccgcagagttgggtggagaaggatttgttgattttgatatcacccaatggtattac
cctgcgaatgcaaaggtcgatgttgctcaattggtagagccatatcgtaatgactgcatt
ttccatgacgcttccggtgcttgccatttcttttttaaagaggtcggcaattggactgta
tctagtattgcattaccatcgaatctcgccaatccgcccatcgattacttccttgacagt
tctagtactgtcattcaaagaattcttcctgcaattcgtgaacacggcatttcatggtcg
tggttacttcagttgatcgctcgcacttggatgaatactttaaagatcgctagccaagct
tctaagaccgaactgttaattgttggtactgcttatgcttgcatgttgatatccattgtg
tctctttaccttaagatgcgtcgtctaggatccaaattttggctattttttagtgtcctg
ctttccactttgttctctgttcaattcgcaatgactttggtacgtgcatctggtgtacgg
attagccttgtctcgttgattgaaagtttgccttttctgataaatgtggttgcccttgat
aaagctgcagaattaacgcggcaagttatcactcgatgctctgtctctgactcccattct
cctatgcatgaagatattgcaaaggcttgccgcaacgctgcaccgcctatcctccgtcat
ttttcttttggaatagtcgttttggcaattttttcgtattgtaattttggtatcaaacaa
ttctttttgtttgctgctgtcatgatttatgatttactcttactgttctctttctttgtc
gccatactcaccctgaaacttgagatgcgccgctataatgctaaggatgatgttcgaaag
gttcttatagaagagggtctctctgagtctacggctcgtcatgttgcagacggcaacgat
tcttcggctactacttctgcagggtcacggtattttaaagttagatatggaaccaaaatc
attcttttcatattcattgccttcaatttgtttgaactttgttctattccgttcaaacat
tatgctgccacttctgctgctgctgctcgattaattcctcttgttcgctctcaatatccc
gattttaagtcacaaaggcttttggatgatggagtgtttgacgacgttctttctgctatt
tcttcaatgtccaacattgaatcaccaagcgtccgtttactaccagctgttttttacggt
gccgaattatccagcacttcttttctatctactatccattcgtttattaacaactggtct
cactacatcagtgcttcgtttttgtcaaaatggatcgtctgtgctttatctttgagtatt
gccgtcaacgtttttcttttgaacgctgctcgattgaactccatcaaagaggaacctgag
aaaaaggtggttgaaaaagttgttgaagtcgttaagtatattccttcgtcgaatagttca
tccattgatgacattcagaaagacgaaatcgctcaagaatccgttgtacgttcgcttgag
gaatgtatcactctttacaacaatggtcaaatttcaactttaaatgatgaagaagttgtg
cagttaaccttagctaaaaaaatccctctttatgctttagaacgagtacttaaagacgtt
accagagctgttgtaattcgccgaacggtcgtctcccgttcatctaggacgaagacactt
gaaagctctaattgccccgtctatcattacgattactctagggttttgaatgcatgttgt
gaaaacgttataggttacatgcccttgccccttggtgtagctggtcctctcattattgac
ggtaagcctttttatatccctatggctactactgagggtgcattggttgcttctactatg
cgtggatgcaaagctattaacgctggtggtggtgctgttactgtattgactcgtgatcaa
atgtcccgtggaccatgtgtggctttcccgaatttgacgcgcgctggtcgtgctaaaatt
tggttggatagccctgaaggccaagaggttatgaagaaggcttttaactctactagccgt
tttgctagacttcaacatattaagactgctctagctggtactcgtcttttcatccgtttc
tgtacgtctaccggtgatgctatgggtatgaatatgatttccaaaggtgttgagcatgca
cttgtagtaatgagcaatgacgctggttttgatgacatgcaagtgatcagtgtatcaggg
aattattgtacagataagaagcctgctgctattaattggattgatggtcgtggtaaaagt
gttattgctgaagctattattcctggtgatgctgtcaaatcggtattgaaaactactgtt
gaagatttggttaaattaaatgttgacaaaaacctcattggtagtgctatggctggcagc
gttggaggatttaatgctcatgctgctaacattgtcacggcagtatatttagcaactggt
caagaccctgcccaaaatgttgaaagcagtaattgtataactttgatggataatgttgat
ggtaaccttcagcttagcgtgtcaatgccatccattgaagttggaacaattggtggtgga
acggttttggaaccgcaaggtgctatgcttgacttgctcggtgtgcgaggtgcccatatg
acctctcccggtgataattctcgtcaactagcacgtgtcgttgcagccgccgtaatggct
ggtgaactgtctttgtgttccgcacttgctagtggccatttagttaaatcccatatcgga
ctcaatcgaagtgcgctgaatactcctgctatggactcttctgccaagaaaccagcgact
gatgctctaaaatccgttaactctcgagtaccgggacgttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   POMBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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